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The interpretation of bone marrow aspiration and histology should provide quantitative information as well as a morphologic assessment of individual cells and cell lines. Most of the bone marrow abnormalities relate to the overall cellularity and/or presence of cell types.
Introduction. 1.1 Indications for Bone Marrow Examination. 1.2 Preliminary Procedures. 1.3 Anatomic site. The Bone Marrow Aspirate. 2.1 Collection of Aspirate Specimens. 2.2 Preparation of Aspirate Slides. 2.3 Preparation of Particle Clots. 2.4 Staining of Bone Marrow Aspirate Slides. 2.5 Microscopy. 2.6 The Nucleated Differential Count.
15 Μαΐ 2015 · Bone marrow (BM) tissue biopsy evaluation, including trephine biopsy and clot section, is an integral part of BM investigation and is often followed by ancillary studies, in particular immunohistochemistry (IHC). IHC provides in situ coupling of morphological assessment and immunophenotype.
3 Μαρ 2024 · A comprehensive laboratory bone marrow examination includes a complete blood count (CBC) and analysis of the peripheral blood smear (PBS), bone marrow aspirate, core biopsy specimen, clot section, and cytometric flow.
Abstract. While a complete blood count provides information regarding possible treatment-related effects reflected in the peripheral blood, morphological evaluation of bone marrow cytology and paraffin sections provides information about bone marrow tissue architecture that otherwise would be missed by examination of peripheral blood alone.
29 Μαρ 2020 · 1 Citations. Abstract. Bone marrow examinations are done for a variety of benign and malignant conditions and are often triggered by abnormalities in the complete blood count and peripheral blood smear. In this chapter, a diagnostic approach to evaluating bone marrows in both adults and children will be reviewed.
4 Σεπ 2008 · Bone marrow smears should be prepared immediately following aspiration. Smears prepared from EDTA samples should be made as soon as possible to reduce storage artefact. To prepare smears, the aspirate should be expelled into a small plastic or siliconized glass dish, and a Pasteur pipette used to draw up particles, which are placed on glass ...
