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6 Φεβ 2019 · The stress theory of aging, sometimes referred to as hormonal theory, supports the notion that the cumulative effects of stress and stressful environments causes disrupts normal cellular function, cause cellular damage, which eventually is expressed in system dysfunction and aging (12).
1 Αυγ 2022 · The findings highlight several key hallmarks of aging that are modified by exposure to chronic stressors and stress hormones, including cellular stress, DNA damage, telomere shortening, inflammation, mitochondrial function, and cellular senescence.
The relationship among stress, hormones, and aging is complex and involves the interplay between three major physiological levels: molecular, cellular, and neuroendo¬crine (1). In this context, the molecular level refers to those intracellular biochemical...
16 Ιουν 2023 · This Scientific Statement was developed to provide a high-level summary of the current state of research across multiple hormonal axes in aging and to identify areas in need of future research. Each section describes the natural history and observational data in older individuals, available therapies, clinical trial data on efficacy and safety ...
The endocrine system plays an important role in coordinating cellular interactions, metabolism, growth, and aging, and scholars have traditionally used endocrine hormone levels as a tool to induce, detect, and validate specific biological effects associated with aging.
8 Μαΐ 2014 · Abstract. The rate of biological aging is modulated in part by genes interacting with stressor exposures. Basic research has shown that exposure to short-term stress can strengthen cellular responses to stress (“hormetic stress”).
7 Φεβ 2019 · adrenal gland that occur during aging are associated with alterations in hormonal output, such as a gradual sustained, increase in glucocorticoid secretion and decline in adrenal androgen...
