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6 Φεβ 2019 · The stress theory of aging, sometimes referred to as hormonal theory, supports the notion that the cumulative effects of stress and stressful environments causes disrupts normal cellular function, cause cellular damage, which eventually is expressed in system dysfunction and aging (12).
1 Αυγ 2022 · This review and guide for research priorities aims to delineate the distinct pathways through which chronic psychosocial stress and the repeated activation of the SNS and HPA axis may directly influence biological aging pathways, and in turn, impact the rate of biological aging.
Mechanisms of Ageing and Development is a multidisciplinary journal aimed at revealing the molecular, biochemical and biological mechanisms that underlie the processes of ageing and development in various species as well as of age-associated diseases.
The relationship among stress, hormones, and aging is complex and involves the interplay between three major physiological levels: molecular, cellular, and neuroendo¬crine (1). In this context, the molecular level refers to those intracellular biochemical...
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16 Ιουν 2023 · This Scientific Statement was developed to provide a high-level summary of the current state of research across multiple hormonal axes in aging and to identify areas in need of future research.
The aging process includes a reduction in GH, and mechanisms linking GH and aging include the evolutionarily conserved insulin/insulin-like growth factor (IGF-1) and rapamycin (mTOR) signaling pathways; these targets are consistent with trade-offs between metabolism, growth, and lifespan.
