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2 Φεβ 2022 · The lysine residues within the human ribosomal protein S17 sequence naturally inserted into the viral nonstructural protein of a unique strain of hepatitis E virus are important for enhanced...
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14 Ιουν 2021 · The most commonly available tests are direct (detection of nucleic acids (i.e., viral genome) or antigens of the virus) and indirect (assessment of serum antibody levels). 2.1. Direct Testing—Molecular Methods
Genomic organization of hepatitis E virus (HEV). The genome of HEV is ∼7.2 kb in length and is composed of a single-stranded positive-sense RNA molecule. The genome contains a 7-methylguanosine RNA cap at the 5′ end and is polyadenylated at the 3′ terminus.
19 Φεβ 2020 · Introduction: Reliable and cost-effective diagnostics for hepatitis E virus (HEV) infection are necessary. The aim of our study was to investigate which diagnostic test is most accurate to detect HEV infection in immunocompetent and immunosuppressed patients in a real world setting.
1 Ιουν 2021 · •. New protocol for HEV sequencing using target enrichment approach would replace limited traditional method. •. The new method is validated for Genotype 1 and 3 and needs further validation using for genotypes 2 and 4.
23 Αυγ 2024 · Diagnosis of HEV infection involves the detection of HEV RNA and anti-HEV IgM/IgG antibodies. Supportive care is the mainstay of treatment for acute infection, while chronic HEV infection may be cleared with the use of ribavirin and pegylated interferon.
8 Σεπ 2021 · As one of the major approaches in combating the COVID-19 pandemics, the availability of specific and reliable assays for the SARS-CoV-2 viral genome and its proteins is essential to identify...
