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Fruits, vegetables, and alcoholic beverages are likely the main sources of exogenous methanol in the healthy human body. Metabolic methanol may occur as a result of fermentation by gut bacteria and metabolic processes involving S-adenosyl methionine.
- Methanol Toxicity - StatPearls - NCBI Bookshelf
Describe the basic pathophysiology and toxicokinetics of...
- Overview: How Is Alcohol Metabolized by the Body? - PMC
Alcohol is eliminated from the body by various metabolic...
- Methanol Toxicity - StatPearls - NCBI Bookshelf
12 Ιουν 2023 · Describe the basic pathophysiology and toxicokinetics of methanol toxicity. Review the examination and evaluation procedures for diagnosing methanol toxicity, including any applicable laboratory testing. Summarize the treatment and management strategy for methanol toxicity.
17 Φεβ 2022 · Methanol is rapidly absorbed from the gastrointestinal tract, distributed to the body water, and is not protein bound. Maximum blood levels are observed within 30 to 60 minutes from ingestion. Toxic methanol levels have also been reported after significant dermal exposure and concentrated inhalation.
Metabolic methanol may occur as a result of fermentation by gut bacteria and metabolic processes involving S -adenosyl methionine. Regardless of its source, low levels of methanol in the body are maintained by physiological and metabolic clearance mechanisms.
Alcohol is eliminated from the body by various metabolic mechanisms. The primary enzymes involved are aldehyde dehydrogenase (ALDH), alcohol dehydrogenase (ADH), cytochrome P450 (CYP2E1), and catalase.
Methanol is a natural by-product of normal metabolism and a major ingredient in the synthesis of organic chemicals, paints, varnish removers, plastics, and coated fabrics. Methanol has also been considered as a major automotive fuel.
Metabolic methanol may occur as a result of fermentation by gut bacteria and metabolic processes involving S-adenosyl methionine. Regardless of its source, low levels of methanol in the body are maintained by physiological and metabolic clearance mechanisms.
