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  1. 24 Ιουλ 2023 · Nociceptive signal transduction to the brain is what elicits the perception of pain. The complex biopsychosocial phenomenon of pain occurs in the cortical and subcortical regions, such as the thalamus, amygdala, hypothalamus, periaqueductal grey, basal ganglia and areas of the cerebral cortex.

  2. Pain is a subjective experience with two complementary aspects: one is a localized sensation in a particular body part; the other is an unpleasant quality of varying severity commonly associated with behaviors directed at relieving or terminating the experience.

  3. Abstract. Pain is an integrative phenomenon that results from dynamic interactions between sensory and contextual (i.e., cognitive, emotional, and motivational) processes. In the brain the experience of pain is associated with neuronal oscillations and synchrony at different frequencies. However, an overarching framework for the significance of ...

  4. 1 Νοε 2021 · Pain sensation leads to suffering via a cognitive (insula), emotional (ACC) and autonomic (ACC plus insula) processing, and is expressed as anger, fear, frustration, anxiety and depression, leading to changes in behaviour and functional disability. Acute pain transitions into chronic pain under influence of genetic and epigenetic factors.

  5. 1 Οκτ 2022 · Ascending spinothalamic and spinoreticular tracts convey pain signals to the brain, where they are processed by the thalamus and sent to the cortex. Descending tracts, via the midbrain periaqueductal grey and nucleus raphe magnus, have a role in pain modulation.

  6. Pain involves a complex interplay between messages sent from the periphery to the central nervous system and vice versa. Specific pathways play a vital role in carrying these messages, and modulating, or exacerbating their downstream effects.

  7. 1 Αυγ 2022 · They found that pressure pain (acute pain) increased brain activity in most of the same brain regions in both groups (e.g., insula, ACC, PFC) while spontaneous pain evoked activity in the PFC and limbic regions (medial PFC, orbitofrontal cortex, accumbens, and amygdala).