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ensure that the owner of a diabetic dog or cat is capable of administering insulin, recognizing the clinical signs of inade-quately managed DM, and monitoring blood glucose levels at home, although this is ideal but not mandatory; all topics that are reviewed in the guidelines. Insulin therapy is the mainstay of treatment for clinical DM.
The glucose curve helps determine: Insulin effectiveness. Maximum and minimum blood glucose levels, which should ideally be between 5 and 14 mmol/l; Glucose nadir (lowest level) goal: 5-8 mmol/l; Duration of insulin effectiveness: Duration of effectiveness used to determine frequency of insulin injections
Estimated ideal body weight, not actual weight, is used to calculate insulin dosages; starting doses should be conservative, not exceeding 2 U/cat. Cats should be reevaluated 5–7 days after starting treatment before adjustments are made to the insulin dosage, unless hypoglycemia develops.
These charts show the curves you would expect to find in a diabetic dog and cat that have little or no clinical signs as well as 4 problem scenarios. Most of the examples below are plotted against over 24 hours but can be easily adapted to a 12-hour timeline. Note: Insulin given at time=0.
CHART: Plot the blood glucose concentrations against time to create the blood glucose curve. Ideal nadir or lowest blood glucose level after insulin administration: 100-125 mg/dL. DOGS. 120-200 mg/dL. CATS. > >250 mg/dL mg/dL. DOGS CATS.
Important Dosage Information. Doses of insulin are measured in units: 40 IU/ml insulin contains 40 International Units (IU) per millilitre (ml). Use Caninsulin with U-40 syringes only to avoid dosing errors when administering Caninsulin to dogs. Human insulin is formulated at a concentration of 100 IU / ml.
10 Μαΐ 2019 · Most dogs are well controlled on insulin at an average dose of 0.5 U/kg q 12 hr with a range of 0.2–1.0 U/kg.The duration of action is close to 12 hr in most dogs, and the amorphous component of the insulin helps to minimize postprandial hyperglycemia.
