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Tocotrienols in animal cells inhibit cholesterol biosynthesis by suppressing 3-hydroxy-3-methyl glutarylCoA reductase enzyme (HMGR): the key-enzyme in the sterologenic pathway, resulting in less cholesterol being manufactured by liver cells.
23 Ιουλ 2021 · Orally administered tocotrienols have shorter elimination half-time by 4.5–8.7 times compared to α-tocopherol . Therefore, twice-daily dosing of tocotrienols supplement is necessary to ensure tocotrienols in the circulating plasma for a sustained period .
20 Νοε 2018 · Tocotrienol Supplements in the Prevention and Treatment of Age-Related Pathologies. Cardiovascular and Metabolic Diseases. Besides to their effect on lipid metabolism, T3 may influence cardiovascular system in other ways.
Therefore, tocotrienols can safely be used for hepatitis C patients, without any side effects. This is first report describing RNA-sequence analysis of δ-tocotrienol treated plasma total mRNAs obtained from chronic hepatitis C patients that acts via multiple-signaling pathways without any side
Tocotrienols, a group of four vitamin E molecules with antioxidant and anti-inflammatory capabilities, reduce inflammation within and improve the function of the lung tissue of animals with cigarette-smoking-induced COPD.
Introduction. Preventing beriberi by eating unpolished rice, curing scurvy by eating citrus fruits, and supporting fertility by eating leafy vegetables—all of these life-sustaining properties of foods are related to factors that in 1912 came to be called vitamins (vita means life).
4 Μαΐ 2023 · Tocotrienols and tocopherols are the biologically active form of vitamin E, which are different in their aliphatic tails. The latter exhibited a superior antioxidant activity as it contains an isoprenoid instead of a phytyl side chain.
