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  1. 24 Αυγ 2023 · The goal of therapy is to correct both the serum sodium and the intravascular volume. Fluids should be administered orally or via a feeding tube whenever possible. In patients with severe dehydration or shock, the initial step is fluid resuscitation with isotonic fluids before free water correction.

  2. 7 Μαρ 2019 · 1 Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic School of Medicine, Rochester, Minnesota. Keywords: Acids; Dehydration; Ions; Noncarboxylic; Potassium; Sodium; diabetes insipidus; diagnosis; hypernatremia; pathophysiology; sodium regulation; treatment; water regulation.

  3. 25 Οκτ 2023 · Treatment of hypernatremia is directed at addressing the underlying cause, as well as replacing free water deficit and ongoing losses while monitoring serum sodium concentration. It is important not to correct the serum sodium concentration too rapidly in cases of chronic hypernatremia.

  4. The review presents the main pathogenetic mechanisms of hypernatremia, provides specific directions for the evaluation of patients with increased sodium levels and describes a detailed algorithm for the proper correction of hypernatremia.

  5. 10 Ιουν 2024 · The treatment of patients with hypernatremia is discussed separately. (See "Treatment of hypernatremia in adults".) Prior to discussing the etiology and evaluation of hypernatremia, it is helpful to review the determinants of the plasma sodium concentration.

  6. Clinical assessment of total body water and urine studies help in determining cause and guiding treatment of hyponatremia. Acute and severe hyponatremia cause neurological symptoms necessitating rapid correction with hypertonic saline.

  7. We review new developments in the pathophysiology of hypernatremia, in addition to the differential diagnosis and management of this important electrolyte disorder. Keywords: TRPV1; diabetes insipidus; hypernatremia; lithium; osmoreceptor; vasopressin.

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