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Management of hypernatremia Basic principles- 1. Identify and treat the underlying cause 2. HR should be corrected slowly (particularly if HR is of unknown duration or chronic) as rapid correction can induce cerebral edema, seizures, permanent neurological damage and death (rate of correction of Na should be <0.5 mmol/l/hour or <12 mmol/l/day).
• Ensure adequate IV access and treat cause of hypernatraemia • If hypovolaemia present, give normal saline as fluid replacement • If/once ECFV is normal, give 5% dextrose or dextrose saline • Reassess clinically and repeat sodium and serum osmolality in 8 hours
We summarize the eight diagnostic steps of the traditional approach and introduce new biomarkers: exclude pseudohypernatremia, confirm glucose-corrected sodium concentrations, determine the extracellular volume status, measure urine sodium levels, measure urine volume and osmolality, check ongoing urinary electrolyte free water clearance, determ...
29 Δεκ 2022 · Moreover, we suggest six steps to manage hypernatremia by replacing water deficits, ongoing water losses, and insensible water losses: identify underlying causes, distinguish between acute and...
27 Ιαν 2016 · Diagnostic approach to hypernatremia is based on the duration of hypernatremia, identification of the cause of fluid loss, assessment of volume status, and urine osmolarity.
Hypernatremia is treated by the administration of free water and/or diuretics, which promote renal excretion of sodium. The rate of correction is critical and must be adjusted to the rapidity of the development of hypernatremia. 2013 Elsevier Inc. All rights reserved. 1. Introduction.
The review presents the main pathogenetic mechanisms of hypernatremia, provides specific directions for the evaluation of patients with increased sodium levels and describes a detailed algorithm for the proper correction of hypernatremia.
