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17 Μαΐ 2024 · This topic will focus on the treatment of hypernatremia induced by water loss, which is the most common cause. The treatment of hypernatremia in patients with impaired thirst, with or without arginine vasopressin disorders, and with primary sodium overload will also be reviewed.
24 Αυγ 2023 · Symptoms and signs of hypernatremia are secondary to central nervous system dysfunction and are seen when serum sodium rises rapidly or is greater than 160 meq/L. Infants and Children present with irritability and agitation, which can progress to lethargy, somnolence, and coma.
The review presents the main pathogenetic mechanisms of hypernatremia, provides specific directions for the evaluation of patients with increased sodium levels and describes a detailed algorithm for the proper correction of hypernatremia.
Treatment of hypernatremia is directed at addressing the underlying cause, as well as replacing free water deficit and ongoing losses while monitoring serum sodium concentration. It is important not to correct the serum sodium concentration too rapidly in cases of chronic hypernatremia.
25 Οκτ 2023 · Hypernatremia represents a deficit of water relative to sodium and can result from a number of causes, including free water losses, inadequate free water intake, and, more rarely, sodium overload. Unlike hyponatremia, hypernatremia is always associated with serum hyperosmolality.
Basic principles. HR should be corrected slowly (particularly if HR is of unknown duration or chronic) as rapid correction can induce cerebral edema, seizures, permanent neurological damage and death (rate of correction of Na should be <0.5 mmol/l/hour or <12 mmol/l/day).
3 Ιαν 2023 · Acute symptomatic hypernatremia, defined as hypernatremia occurring in a documented period of less than 24 hours, should be corrected rapidly. Chronic hypernatremia (> 48 h), however, should be...
