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  1. 17 Μαΐ 2024 · This topic will focus on the treatment of hypernatremia induced by water loss, which is the most common cause. The treatment of hypernatremia in patients with impaired thirst, with or without arginine vasopressin disorders, and with primary sodium overload will also be reviewed.

  2. With hypernatremia, there’s a higher than normal concentration of sodium in the blood - above 145 milliequivalents per liter. However, since the concentration of sodium depends on both sodium and water levels in the body, hypernatremia actually translates as too little water in the extracellular compartment.

  3. 25 Οκτ 2023 · Treatment of hypernatremia is directed at addressing the underlying cause, as well as replacing free water deficit and ongoing losses while monitoring serum sodium concentration. It is important not to correct the serum sodium concentration too rapidly in cases of chronic hypernatremia.

  4. 5 Ιουλ 2024 · The cornerstone of hypernatremia treatment is free water replacement. There are two general strategies to achieve this: Ad librium strategy : For alert patients with mild-moderate hypernatremia who are thirsty and able to drink, the best treatment is to simply provide them with free access to water.

  5. The review presents the main pathogenetic mechanisms of hypernatremia, provides specific directions for the evaluation of patients with increased sodium levels and describes a detailed algorithm for the proper correction of hypernatremia.

  6. Management of hypernatremia Basic principles- 1. Identify and treat the underlying cause 2. HR should be corrected slowly (particularly if HR is of unknown duration or chronic) as rapid correction can induce cerebral edema, seizures, permanent neurological damage and death (rate of correction of Na should be <0.5 mmol/l/hour or <12 mmol/l/day).

  7. General Management. Treat underlying cause once identified. This is as important as treatment of hypernatraemia. Mild cases of hypernatraemia - replace missing body water with oral water (not electrolyte drinks) or glucose 5% IV.

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