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1 Μαρ 2017 · A downward shift of the TSH reference range occurs during pregnancy, with a reduction in both the lower (decreased by about 0.1–0.2 mU/L) and the upper limit of maternal TSH (decreased by about 0.5–1.0 mU/L), relative to the typical nonpregnant TSH reference range.
11 Αυγ 2023 · Women found to have a TSH level greater than 10 mIU/L in the first trimester of pregnancy should be treated for hypothyroidism. Conversely, women with a TSH of 2.5 or less, do not need levothyroxine treatment.
Overt hypothyroidism in pregnancy is identified when TSH > 10 mIU/L, and treatment with LT4 is readily recommended at an initial dose of 2 mcg/kg/day.
15 Ιαν 2017 · New evidence-based recommendations from the American Thyroid Association (ATA) provide guidance to clinicians in diagnosing and managing thyroid disease during pregnancy and the postpartum period. Pregnancy has a profound effect on thyroid gland function, and thyroid disease is common in pregnancy.
Overall then, TSH tends to be lower than usual with a transient rise in free T4 levels during the 1st trimester. TSH then normalises for the rest of pregnancy, and there is a modest fall in Free T4 in 2nd and 3rd trimester, but still within normal ranges; free T3 levels are similar.
Download Full Issue. Management of Hypothyroidism and Hypothyroxinemia During Pregnancy. Elizabeth N. Pearce, MD, MSc elizabeth.pearce@bmc.org. Download PDF. Abstract. Objective. To review the diagnosis and management of hypothyroidism during pregnancy, in the preconception period, and in the postpartum period. Methods.
Clinical Algorithm for Management of Thyroid Disease in Pregnancy. Abbreviations: T 3 , triiodothyronine; T 4 , thyroxine; TRAB, thyroid receptor antibodies; TSH, thyroid-stimulating hormone; TSI, thyroid-stimulating immunoglobulin.
