Αποτελέσματα Αναζήτησης
1 Σεπ 2022 · IgD myeloma was historically associated with worse outcomes, but we now report a standard cytogenetic risk profile and survival outcomes. Improved IgD myeloma survival is due to earlier diagnosis, improved supportive care, and response to novel antimyeloma therapies.
20 Οκτ 2022 · Immunoglobulin D-secreting multiple myeloma (IgD MM) is a rare form of the disease, accounting for approximately 1–2% of cases. Its frequency is possibly underestimated because of a protein immunochemistry workup lacking full discretionary reflex testing.
IgD has antibody activity to specific antigens (34, 53, 60, 109, 110); individuals with high levels of IgD can produce specific IgD antibodies after antigenic challenge .
28 Ιουν 2021 · This review will concentrate on major progress in expressions, functions, and mechanisms of tumor-derived Igs, similarities and differences between tumor-derived Igs and B-cell-derived Igs.
7 Μαΐ 2018 · The enigma of dual IgD and IgM expression has been tackled by several recent studies showing that IgD helps peripheral accumulation of physiologically autoreactive B cells through its functional unresponsiveness to self-antigens but prompt readiness against foreign antigens.
Studies on the ability of IgD to function as a chemotactic agent (the so-called cytotaxigen or cytotaxinogen) found that IgD could induce the infiltration of myeloid cells, mainly composed of neutrophils and low numbers of eosinophils but not lymphoid cells, into skin at an early stage of inflammation in patients with contact dermatitis but not ...
17 Ιουλ 2019 · Objective: Immunoglobulin D (IgD) levels are often elevated in patients with autoimmune diseases. However, the oncogenic activities of IgD and IgD receptor (IgDR) in diffuse large B-cell lymphoma (DLBCL) have not been reported in detail.
