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7 Μαΐ 2018 · Secreted IgD appears to enhance mucosal homeostasis and immune surveillance by “arming” myeloid effector cells such as basophils and mast cells with IgD antibodies reactive against mucosal antigens, including commensal and pathogenic microbes.
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Eur. J. Immunol. 2018. 48: 1101–1113 DOI:...
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Immunoglobulin D (IgD) has remained an enigmatic antibody class since its discovery almost 50 years ago. Because of its spotty presence in mammals and absence in birds, IgD was initially thought to be a recently evolved Ig isotype.
1 Ιουν 2014 · Internet gaming disorder (IGD) has received nomenclatural recognition as a potential mental health disorder, despite evident variability in its core psychopathology and psychometric assessment.
Immunoglobulin D (IgD) is a type of antibody produced by B cells that plays a crucial role in cell signaling on the cell membrane. Despite being present in small amounts in the serum, IgD does not have a significant function in host defense mechanisms.
Immunoglobulin D (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes where it is usually co-expressed with another cell surface antibody called IgM.
17 Οκτ 2018 · This study demonstrates that secreted IgD promotes protective humoral responses to soluble antigens such as food allergens.
The enigma of dual IgD and IgM expression has been tackled by several recent studies showing that IgD helps peripheral accumulation of physiologically autoreactive B cells through its functional unresponsiveness to self-antigens but prompt readiness against foreign antigens.
