Αποτελέσματα Αναζήτησης
29 Ιουλ 2016 · These trials demonstrate that substantial protection against HSV disease and herpes zoster can be induced by recombinant viral proteins combined with an adjuvant that induces the appropriate adaptive (T and B cell) immune response, by targeting innate immune antigen-presenting cells.
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Incremental advances in our knowledge of how natural immune...
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Incremental advances in our knowledge of how natural immune...
- Laser Vaccine Adjuvant for Cutaneous Immunization
Adjuvant for cutaneous vaccination. At present, the majority...
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An HSV-2 type-specific CD4 + clone (EA.17) from the cervix...
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14 Δεκ 2023 · In a study of lab-engineered cells, Harvard Med researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction.
In this article we will review the innate immune mechanisms that are known to impact HSV infection, the evasion strategies utilized by HSV to over come these responses, and the disease manifestations that result from immune deficiencies. There are two species of HSV, HSV-1 and HSV-2.
18 Αυγ 2021 · This immediate innate immune response provides the most proximal defense and includes the accumulation of antiviral proteins, such as IFN-stimulated genes (ISGs), as well as a variety of protective cytokines.
25 Ιαν 2011 · Innate immune defence against herpesviruses is highly dependent on the type I interferon system and natural killer cells. Model studies in mice and genetic data from humans have revealed...
This review focuses on the immune system response to HSV-1 infection. Particular emphasis is placed on the evidence pointing to the HSV-1-specific CD8(+) T cells in the trigeminal belonging to the TRM class of memory T cells and the role of TRM cells in virus infection, pathogenesis, latency, and disease.
8 Ιουλ 2022 · Genital herpes infections are associated with morbidity, transmission to the neonate, and enhanced transmission of human immunodeficiency virus-1 (HIV-1) [1–3]. Development of effective strategies to interrupt transmission and decrease prevalence in adults will require an understanding of disease transmission and natural history, as well as ...
