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There are two species of HSV, HSV-1 and HSV-2. Viruses of both species cause ulcerative lesions at oral (usually HSV-1) and genital (usually HSV-2 but increasingly HSV-1) mucosae, and HSV innate immune evasion mechanisms likely contribute to viral spread and extent of disease at these mucosal sites.
14 Δεκ 2023 · In a study of lab-engineered cells, Harvard Med researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction.
18 Αυγ 2021 · Herein, we review the current literature that highlights human herpesvirus inhibition and exploitation of the innate immune responses, using herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Kaposi’s sarcoma-associated herpesvirus (KSHV) as examples.
13 Φεβ 2024 · This article explains the symptoms of a herpes skin rash and explores its causes and treatments. It also examines some other possible causes of skin complaints that may look similar to...
15 Ιουλ 2024 · Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. It can also cause infection in the eye, skin, central nervous system, and/or visceral organs. This topic will review treatment and prevention of primary and recurrent HSV-1 infections in immunocompetent adolescents and adults.
29 Ιουλ 2016 · Development of a prophylactic vaccine for herpes simplex virus types 1 and 2 (HSV1 and 2) is a WHO-supported global public health priority because (1) genital herpes caused by HSV1/2 is now the commonest sexually transmitted infection and causes severe disease in neonates; (2) HSV1 is the leading cause of infectious blindness in western countrie...
Abstract. Vitamin D is renowned for its pleiotropic effects, including but not limited to bone integrity, and it has assumed an important role in the current research era. As vitamin D receptors are present in a variety of human tissues, particularly immune cells, the immunomodulatory potential of vitamin D cannot be overemphasized.
