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1 Δεκ 2001 · This review evaluates the functional and molecular evidence that the inhibin α subunit is a tumor suppressor in endocrine cancers. The evaluation highlights the discrepant results from the human and mouse studies, as well as the differences between endocrine tumor types.
15 Δεκ 2022 · Inhibin A levels are highest during the late follicular and luteal phases of a normal menstrual cycle, whereas inhibin B dominates in the early and mid follicular phases and declines in the late follicular phase [9, 10].
Nevertheless, taken together, recent findings suggest that it may be more appropriate to consider a new paradigm for inhibin, activin, and FS in which activin signaling is regulated extracellularly by both inhibin and FS whereas a number of intracellular proteins act to modulate cellular responses to these activin signals.
In this review, we provide a comprehensive summary of our current understanding of the biological role of inhibin, its relationship with activin, its signaling mechanisms, and its potential value as a diagnostic marker for reproductive function and pregnancy-associated conditions.
21 Ιαν 2021 · Inhibin A and inhibin B tumor marker tests measure these blood hormone levels to help detect a rare ovarian granulosa cell tumor.
28 Ιουν 2021 · In summary, Inhibin B is a promising biomarker for judging the state of testicular spermatogenesis, which can be a good biomarker for clinical doctors to screen non‐obstructive azoospermia patients from obstructive azoospermia patients.
The American Physiological Society Journal publishes research on various aspects of physiology, including cell biology, renal function, and neural activity.
