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1 Μαΐ 2023 · INR monitoring is most commonly required for the patients who are on warfarin, a vitamin K antagonist. The dose of warfarin is adapted based on INR scores so that it remains in the therapeutic range to prevent thrombosis from subtherapeutic INR or hemorrhagic complications from supratherapeutic INR.
5 Οκτ 2024 · Close monitoring of prothrombin time (PT) and the international normalized ratio (INR) is essential to ensure therapeutic effectiveness and minimize adverse events, such as bleeding. This activity reviews the pharmacokinetics, drug interactions, and adverse event profile of warfarin.
27 Ιουν 2023 · If the INR is below the target range, a person is considered under-anticoagulated, and there is an increased risk of clotting. If the INR is above the target range, the person is considered over-anticoagulated, and there is an increased risk of bleeding.
18 Απρ 2017 · The time in the therapeutic range (an international normalized ratio [INR] between 2.0 and 3.0) (TTR) has been used as a measure of warfarin (W) therapy quality.
3 Μαρ 2009 · It is important to monitor the INR (at least once a month and sometimes as often as twice weekly) to make sure that the level of warfarin remains in the effective range. If the INR is too low, blood clots will not be prevented, but if the INR is too high, there is an increased risk of bleeding.
The warfarin therapeutic range refers to the target international normalized ratio (INR) values at which the anticoagulant effect of warfarin is deemed effective in preventing thromboembolic events while minimizing the risk of bleeding complications.
Warfarin treatment is usually long term. If the person is going to have cardioversion, the target international normalized ratio (INR) should be achieved at least 3 weeks before cardioversion and 4 weeks after (if normal sinus rhythm is maintained).
