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The use of warfarin is declining with preference now being given to direct oral anticoagulants (DOACs) as first-line therapy in common anticoagulation indications, such as VTE treatment and prevention of recurrence, and stroke prevention in non-valvular atrial fibrillation (NVAF).
1 Μαΐ 2023 · INR monitoring is most commonly required for the patients who are on warfarin, a vitamin K antagonist. The dose of warfarin is adapted based on INR scores so that it remains in the therapeutic range to prevent thrombosis from subtherapeutic INR or hemorrhagic complications from supratherapeutic INR.
23 Αυγ 2024 · Choose your therapeutic INR range and refer to the INR warfarin chart to check recommendations for your patient's actual INR level. Get to know your patient's daily warfarin dose. Calculate your patient's weekly warfarin dose.
27 Ιουν 2023 · If the INR is below the target range, a person is considered under-anticoagulated, and there is an increased risk of clotting. If the INR is above the target range, the person is considered over-anticoagulated, and there is an increased risk of bleeding.
For most indications, the therapeutic INR range is 2.0 to 3.0. Exceptions are when war-farin is used for secondary prevention after a myocardial infarction or for patients with high-risk mechanical prosthetic heart valves, in which case the range is 2.5 to 3.5.
This guideline outlines the evidence for managing anticoagulation therapy with oral vitamin K antagonist (warfarin). For dosing and monitoring of warfarin therapy it is recommended that standardized and validated decision support tools be used for most patients.
3 Μαρ 2009 · It is important to monitor the INR (at least once a month and sometimes as often as twice weekly) to make sure that the level of warfarin remains in the effective range. If the INR is too low, blood clots will not be prevented, but if the INR is too high, there is an increased risk of bleeding.
