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1 Μαΐ 2023 · INR monitoring is most commonly required for the patients who are on warfarin, a vitamin K antagonist. The dose of warfarin is adapted based on INR scores so that it remains in the therapeutic range to prevent thrombosis from subtherapeutic INR or hemorrhagic complications from supratherapeutic INR.
5 Οκτ 2024 · For patients with caged ball or caged disk valves, warfarin therapy should also target an INR of 3.0, with a range of 2.5 to 3.5. For patients with a bioprosthetic mitral valve, warfarin therapy should maintain a target INR of 2.5 (range, 2.0 to 3.0) for the first 3 months post-implantation.
27 Ιουν 2023 · In most cases the target INR range will be between 2 and 3, although other ranges may be chosen if there are special circumstances. In a person who is not taking warfarin, the INR would be approximately 1.
10 Φεβ 2021 · The use of warfarin is declining with preference now being given to direct oral anticoagulants (DOACs) as first-line therapy in common anticoagulation indications, such as VTE treatment and prevention of recurrence, and stroke prevention in non-valvular atrial fibrillation (NVAF).
3 Μαρ 2009 · It is important to monitor the INR (at least once a month and sometimes as often as twice weekly) to make sure that the level of warfarin remains in the effective range. If the INR is too low, blood clots will not be prevented, but if the INR is too high, there is an increased risk of bleeding.
25 Ιουλ 2024 · Time spent with a prothrombin time/international normalized ratio (PT/INR) above the therapeutic range increases the risk of bleeding, and time spent below the therapeutic range increases the risk of thromboembolic complications.
The warfarin therapeutic range refers to the target international normalized ratio (INR) values at which the anticoagulant effect of warfarin is deemed effective in preventing thromboembolic events while minimizing the risk of bleeding complications.
