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  1. 3 Μαρ 2009 · It is important to monitor the INR (at least once a month and sometimes as often as twice weekly) to make sure that the level of warfarin remains in the effective range. If the INR is too low, blood clots will not be prevented, but if the INR is too high, there is an increased risk of bleeding.

  2. 18 Απρ 2017 · The time in the therapeutic range (an international normalized ratio [INR] between 2.0 and 3.0) (TTR) has been used as a measure of warfarin (W) therapy quality.

  3. 20 Οκτ 2020 · Background. The use of warfarin in patients with non-valvular atrial fibrillation (NVAF) can be challenging. In this study, we evaluate the time in therapeutic range (TTR), health-related quality of life (HRQoL) and treatment satisfaction of patients on long-term warfarin for NVAF.

  4. 31 Ιουλ 2012 · In most cases, an INR between 2 and 3 indicates that the warfarin dose is about right. In one large study, 1 the risk of stroke caused by a blood clot increased 3 to 4 times when the INR was between 1.4 and 1.7 (not enough warfarin).

  5. 16 Δεκ 2011 · Comment: The duration of time a patient’s international normalized ratio (INR) is maintained within the therapeutic range (time in the therapeutic range, TTR) for his or her particular indication for the drug impacts the effectiveness and safety of warfarin therapy.

  6. The time in therapeutic range (TTR) is a commonly used quality measure for anticoagulation therapy with warfarin. Maximizing TTR has been shown to provide the most benefit for preventing stroke, major hemorrhage, and death.

  7. Mean TTR over 180 days after VTE was lowest for patients <60 kg (TTR 180 [mean ± SD]: <60kg: 49.3% ± 24.2% vs ≥60 to <100 kg: 57.8% ± 23.4%; P < .0001). For DOAC-treated patients over 180 days after index VTE, mean PDC was lowest for patients <60 kg (PDC 180 [mean ± SD]: < 60kg: 76.9% ± 33.2% vs ≥ 60 to <100 kg: 83.6% ± 27.7%; P < .0001).

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