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Antibiotic treatment for rheumatoid arthritis (RA) commenced in the 1930s with the use of sulfasalazine. Later, tetracyclines were successfully used for the treatment of RA. In double-blind and randomized studies, levofloxacin and macrolide antibiotics (including clarithromycin and roxithromycin) were also shown to be effective in the treatment ...
- Role of Doxycycline as an Osteoarthritis Disease-Modifying Drug
Doxycycline is a tetracycline antibiotic that has been shown...
- Role of Doxycycline as an Osteoarthritis Disease-Modifying Drug
Doxycycline is a tetracycline antibiotic that has been shown to induce the inhibition of cartilage matrix metalloproteinases (MMPs) and slow down the progression of structural damage to the affected joint . It was hence recommended as a disease-modifying therapy for OA.
29 Ιαν 2021 · Doxycycline and minocycline are tetracyclines that are well studied for their efficaciousness in inhibiting inflammatory mediators that could contribute to the progression of arthritis. Recent reviews have found minocycline to be a promising drug in the treatment of chronic pain [ 16 ].
23 Απρ 2024 · Doxycycline is a broad-spectrum tetracycline antibiotic that may be taken within 72 hours of unprotected sex to help prevent common STDs, such as syphilis, chlamydia, and gonorrhea. This is known as the STD morning-after-pill or Doxy PEP.
Pre-clinical data suggest that doxycycline might act as a disease-modifying agent for the treatment of osteoarthritis, with the potential to slow cartilage degeneration. This is an update of a Cochrane review first published in 2009.
It also is used for the treatment of non-gonococcal urethritis (due to Ureaplasma), Rocky Mountain spotted fever, typhus, chancroid, cholera, brucellosis, anthrax, syphilis, acne, and periodontal disease. Tetracycline is a broad-spectrum antibiotic, that is, it is active against many different types of bacteria.
14 Μαΐ 2009 · Doxycycline is a member of the tetracycline class of antibiotics and has been used clinically for more than 40 years. It is a well-tolerated drug that is bacteriostatic and acts via the inhibition ...
