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16 Οκτ 2019 · Ependymomas are glial cell tumors that commonly arise in the lining cells of the ventricular system, and less commonly outside the central nervous system (CNS), or within the brain parenchyma. They are comprised of genetically distinct subgroups of tumors and affect children more commonly than adults.
1 Ιουλ 2024 · Genetics. People with a genetic disease called neurofibromatosis type 2, which cause tumors to form on nerve tissue, have a significantly increased chance of developing an ependymoma. NF2 is inherited genetically, and those with the disease have an increased chance of developing many other types of CNS tumors.
21 Απρ 2023 · Ependymoma is a growth of cells that forms in the brain or spinal cord. The cells form a mass called a tumor. Ependymoma begins in the ependymal cells. These cells line the passageways that carry cerebrospinal fluid. This fluid surrounds and protects the brain and spinal cord.
31 Μαΐ 2022 · What is an ependymoma? An ependymoma is a mass of irregular cells (tumor) in your brain or spinal cord. It’s a type of primary central nervous system tumor. Ependymomas start in your brain or spinal cord instead of starting elsewhere and spreading to your brain or spinal cord.
14 Ιαν 2022 · This Review discusses important biological features of ependymoma as well as key oncogenes, tumour suppressors and epigenetic changes that could potentially be exploited to improve therapy.
28 Μαρ 2016 · Ependymomas are rare primary tumors of the central nervous system in children and adults that comprise histologically similar but genetically distinct subgroups. The tumor biology is typically more associated with the site of origin rather than being age-specific.
1 Δεκ 2022 · Except for recurrent chromosomal aneuploidies, no specific biological features were identified in ependymoma for decades. During the last years, specific, primary genetic alterations, associated with distinct tumour subtypes, have been described.
