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In the past 5 years, many researchers have conducted in‐depth studies into the pathogenesis of endemic fluorosis. Research in the areas of fluoride‐induced stress pathways, signalling pathways and apoptosis has provided further extensive knowledge at the molecular and genetic level.
Damage to the soft tissues due to high doses of fluoride may occur when it passes through the blood-brain, blood-testis, and blood-placenta barrier. Thus, various treatment approaches have been recommended for dental fluorosis patient depending on the severity of the disease.
1 Νοε 2021 · Defluoridation techniques like the Nalgonda technique, reverse osmosis (RO), and adsorption using activated alumina have found to be promising to reduce fluoride concentration within the prescribed limits, and RO water is most widely used for drinking in fluorosis affected regions.
Fluorosis is a condition that occurs when you ingest too much fluoride over a long period of time. Types include dental fluorosis and skeletal fluorosis.
12 Ιουλ 2021 · Excessive fluoride intake is associated with damage to the tissues and cells due to the inhibition of few metabolic enzymes and causes pro and antioxidant imbalance. Fluorosis causes ROS, RNS and is the most prevalent cause of oxidative damage of phospholipids in the plasma membrane.
fluorosis, due to fluoride ion (F) toxicity, in out-patient departments, by retrieving the history and through tests and (ii) the interventions available for recovery. In patients suspected of fluorosis, the F levels were investigated in samples of drinking water and body fluids (serum and urine), and fore-arm X-ray radiographs taken to assess the
Fluorosis is a progressive degenerative disease that causes skeletal fluorosis and dental fluorosis.1 Previous studies have shown that fluoride can cross the blood–brain barrier, induce neurotoxicity, and affect children's cognitive abilities and mental development. 2–4 Currently, about 500 million people are exposed to environments high in fluo...
