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The test measures the amount of free kappa and lambda light chains in the blood and calculates a kappa/lambda ratio. It does this to help detect, diagnose, and monitor conditions associated with an increased production of free light chains (FLC).
A free light chains test measures the amount of lambda and kappa free light chains in the blood. If the amount of free light chains is higher or lower than normal, it can mean you have a disorder of the plasma cells.
A kappa free light chain test is a quick blood test that measures certain proteins in your blood. High levels of these proteins may mean you have a plasma cell disorder. A healthcare provider might order a kappa free light chain test if you have symptoms such as bone pain or fatigue.
19 Νοε 2010 · The serum free light chain (FLC) assay quantitates free kappa and free lambda immunoglobulin light chains. This assay has prognostic value in MGUS, multiple myeloma (MM), solitary plasmacytoma, and amyloid light chain (AL) amyloidosis, and has been incorporated in response criteria for both MM and AL amyloidosis.
22 Οκτ 2018 · Free light chains refer to those that are not part of whole (= intact) immunoglobulins and are present in the blood. This test measures the amount of free kappa and light chains in the blood to help detect, diagnose, and monitor conditions associated with an increased production of free light chains.
2 Νοε 2023 · Background: Serum free light chain (FLC) measurement, consisting of serum free kappa, serum free lambda, and a calculated FLC ratio (kappa/lambda), plays a pivotal role in the diagnosis, risk stratification and management of plasma cell disorders.
Although this guide is extremely useful in assessment for myeloma there are other result patterns particularly on sFLC assessment that can appear abnormal. Each sFLC report includes a result for the level of the Kappa and Lambda light chains and for the ratio of Kappa to Lambda.
