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A pancreatic islet from a mouse in a typical position, close to a blood vessel; insulin in red, nuclei in blue. The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. [1]
The islets of Langerhans are irregularly shaped patches of endocrine tissue located within the pancreas of most vertebrates. They are named for the German physician Paul Langerhans, who first described them in 1869.
29 Σεπ 2015 · Here we show that islets are spread gradually from the head up to the tail section of the pancreas in the form of contracted or dilated islet routes. We also report a particular anatomical...
The pancreatic islets are small islands of cells that produce hormones that regulate blood glucose levels. Hormones produced in the pancreatic islets are secreted directly into the bloodstream by five different types of cells. The alpha cells produce glucagon, and make up 15–20% of total islet cells.
3 Οκτ 2022 · The islets of Langerhans are clusters of pancreatic cells discovered by Dr. Paul Langerhans, a pathologist who also discovered the dendritic Langerhans cells in 1869. [1] Each islet contains up to a few thousand endocrine cells, and the islets constitute up to 2% of the total pancreatic mass.
18 Νοε 2019 · Pancreatic islets, which are critical for glucose homeostasis, are endocrine microorgans embedded in the exocrine pancreas; their location has often limited studying their function.
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and their dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and that is well vascularized and innervated.
