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The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. [1]
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym (s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets. Langerhans cell granulomatosis.
i's of Langerhans (pancreatic i's) irregular microscopic structures scattered throughout the pancreas and comprising its endocrine portion. They contain the alpha cells, which secrete the hyperglycemic factor glucagon; the beta cells, which secrete insulin, and whose degeneration is one of the causes of diabetes mellitus ; and the delta cells ...
The pancreatic islets are small islands of cells that produce hormones that regulate blood glucose levels. Hormones produced in the pancreatic islets are secreted directly into the bloodstream by five different types of cells. The alpha cells produce glucagon, and make up 15–20% of total islet cells.
8 Αυγ 2023 · Pancreatic islet cell transplantation is performed to prevent unrecognized hypoglycemia in type I diabetics. The procedure involves placing Islet cells into the portal vein via ultrasound or fluoroscopic guidance; laparoscopic placement has also been described.
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and their dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and that is well vascularized and innervated.
Pancreatic islets, or islets of Langerhans, are mini-organs, each composed of a few dozen to several thousands of pancreatic endocrine cells [1]. Approximately 1 million islets are distributed throughout the human pancreas [2].
