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  1. Thirty-seven patients with chronic, stable angina pectoris were included in a randomized, double-blind cross-over study to assess the efficacy of once- and twice-daily dosage regimens of 60 mg isosorbide-5-mononitrate, in a controlled-release formulation (5-ISMN Durules, Astra).

  2. 4 Αυγ 2023 · Consider 5 mg twice daily for small statured patients; increase to at least 10 mg twice daily in first 2 to 3 days. Asymmetric dosing (7 hours apart) provides a nitrate-free interval to minimize tolerance. Start at the low end of the dosing range for elderly patients.

  3. Angina Pectoris. Prevention of angina pectoris caused by coronary artery disease. Immediate release: 5-10 mg PO twice daily initially (5 mg in small patients) given each dose 7 hr apart;...

  4. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). It does not work fast enough to relieve the pain of an angina attack that has already started. Isosorbide mononitrate belongs to the group of medicines called nitrates.

  5. 14 Αυγ 2023 · Isosorbide mononitrate is used to prevent angina attacks (chest pain) by dilating blood vessels, making it easier for blood to flow - includes isosorbide mononitrate side effects, interactions and indications.

  6. For example, if you're taking standard tablets twice a day, they may tell you to take 1 dose in the morning at 8am and the second dose in the afternoon at 2pm (leaving a gap of 6 hours between your first and second dose).

  7. Angina. Isosorbide dinitrate or mononitrate is used for the acute relief of angina pectoris, for prophylactic management in situations likely to provoke angina attacks, and for long-term prophylactic management of angina pectoris.

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