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  1. 16 Μαΐ 2023 · It is in the nitrate class of drugs. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced ejection fraction, and achalasia.

  2. pubmed.ncbi.nlm.nih.gov › 32491771Isosorbide - PubMed

    16 Μαΐ 2023 · This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced ejection fraction, and achalasia.

  3. According to the clinical observations in this study, the intravenous drip of ISMN is fast-acting with good absorption, high bioavailability, clear efficacy and high safety in the treatment of angina pectoris in coronary heart disease.

  4. 10 Δεκ 2015 · Isosorbide mononitrate or placebo was initiated at a dose of 30 mg daily for 1 week and 60 mg daily for 1 week before reaching the target dose of 120 mg daily.

  5. 4 Φεβ 2024 · Isosorbide levels in biological samples were quantified based on the analytical method using gas chromatography-mass spectrometry (GC-MS). Following administration, isosorbide exhibited rapid absorption and elimination, with a bioavailability of 96.1%.

  6. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced ejection fraction, and achalasia.

  7. Isosorbide dinitrate (ISDN) is the most commonly used nitrate, and it quickly relieves angina pectoris within a few minutes of sublingual administration. The initial sublingual dose of 5-10 mg is given for a single time.

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