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16 Μαΐ 2023 · Isosorbide is used to manage anginal pain due to coronary artery disease, and it has approval for use in heart failure. The challenges of isosorbide therapy are drug interactions, adverse effects, and the development of tolerance during chronic isosorbide therapy.
16 Μαΐ 2023 · This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced ejection fraction, and achalasia.
Isosorbide | C6H10O4 | CID 12597 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
ISDN has a short half-life and is primarily effective clinically by metabolism to the active metabolite isosorbide-5-mononitrate, which has an average half-life of 5 hours. This is the active ingredient in the two new nitrate preparations Imdur and Ismo.
31 Μαΐ 2011 · Isosorbide dinitrate (ISDN) is an NO donor, and hydralazine has antioxidant properties; this combination has the potential to restore the disrupted nitroso-redox balance and to reverse the disrupted NO signaling.
Isosorbide dinitrate (ISDN) is the most commonly used nitrate, and it quickly relieves angina pectoris within a few minutes of sublingual administration. The initial sublingual dose of 5-10 mg is given for a single time.
1 Αυγ 1991 · Background: To define better the efficacy of vasodilator therapy in the treatment of chronic congestive heart failure, we compared the effects of hydralazine and isosorbide dinitrate with those of enalapril in 804 men receiving digoxin and diuretic therapy for heart failure.
