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  1. 1 Φεβ 2024 · Revision, Clinical Modification (ICD -10-CM). These guidelines should be used as a companion document to the official version of the ICD-10-CM as published on the NCHS website. The ICD-10-CM is a morbidity classification published by the United States for classifying diagnoses and reason for visits in all health care settings. The ICD-

  2. See Table 5 for recommendations for TDM for itraconazole. Recommendation 1: TDM should be performed in the majority of patients receiving itraconazole. The evidence for the potential clinical benefits of TDM for patients receiving itraconazole is strong, but largely circumstantial.

  3. 1 Οκτ 2022 · Itraconazole is an FDA-approved anti-fungal drug of the triazole class, and has been used clinically for more than 30 years. Recent drug repurposing screens revealed itraconazole exerts anti-cancer activity via inhibiting angiogenesis and multiple oncogenic signaling pathways.

  4. 15 Απρ 2015 · Itraconazole (ITZ) is a triazole anti-fungal treatment widely used in the prevention and systemic treatment of a broad range of fungal infections, including aspergillosis, blastomycosis, candidiasis, histoplasmosis, and in some dermatological and nail infections.

  5. These guidelines provide recommendations on antifungal drug monitoring and TDM-guided dosing adjustment for selected antifungal agents, and include suggested resources for identifying and analysing antifungal drug interactions.

  6. 29 Δεκ 2013 · The strongest evidence to support TDM of itraconazole is for the prevention of invasive fungal infections in profoundly immunocompromised patients. Many early clinical studies analysing the efficacy of itraconazole were inconclusive, predominantly because they were underpowered.

  7. support the use of TDM for itraconazole, voriconazole, posaconazole, fl. cytosine. and isavuconazole. TDM of fluconazole is not routin. describ. d in above table should guide the fr. References. Papers of particular interest, published recently, have been highlighted as: *Of major importance. rapeutic drugconcentrations of isavuconazole fol.