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Iron sucrose injection is an iron replacement product that is used to treat iron deficiency anemia (not enough iron in the blood) in patients with chronic kidney disease (CKD). Iron is a mineral that the body needs to produce red blood cells.
We explored potential sources of heterogeneity: type of IV iron preparation, comparator (placebo, oral, no iron, IM iron, or other), indication for iron therapy, adequacy of collecting and reporting methods of the AEs, and the adequacy of allocation generation, concealment, and masking.
Objective: To amass all available evidence regarding the safety of intravenous (IV) iron preparations to provide a true balance of efficacy and safety. Methods: Systematic review and meta-analysis of all randomized clinical trials comparing IV iron to another comparator.
4 Δεκ 2010 · This section reviews the history, pharmacology, administration, efficacy, and toxicity of intravenous iron. Intravenous iron offers advantages over oral iron for the treatment of iron deficiency anemia across a wide range of disease states associated with absolute and functional iron deficiency.
5 Νοε 2021 · Oral iron is the first-line therapy for treating iron deficiency anemia; intravenous(IV) iron is used when oral iron is inappropriate, poorly tolerated or ineffective. The major adverse effect associated with IV iron is infusion-related reactions (IRR), ranging from mild reactions mediated by complement activation-related pseudo-allergy to ...
Intravenous (IV) iron is increasingly used for the treatment of iron deficiency anemia (IDA) when oral iron is ineffective or poorly tolerated and when it or blood transfusion is inappropriate. 1, 2 It is also indicated in combination with erythropoiesis-stimulating agents in chronic kidney disease and chemotherapy-induced anemia.
29 Ιαν 2024 · This comprehensive consensus provides step-by-step guidance and tools for practitioners to promote safe delivery of intravenous iron, recognition, and management of infusion reactions and treatment-emergent hypophosphatemia.
