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11 Φεβ 2017 · It is common practice to provide an initial course of IV iron amounting to approximately 1000 mg; this may be repeated if an initial dose fails to increase Hb level and/or allow a decrease in ESA dose and if the TSAT remains ≤30% and serum ferritin remains ≤500 ng/ml (≤500 mcg/l).
IV iron sucrose (Venofer®) given as a divided dose, and low molecular weight iron dextran (CosmoFer®) this can be given as a total dose infusion (CosmoFer ® may also be given intramuscularly).
The decision to use intravenous iron in place of oral iron should be discussed with a senior clinician experienced in the management of iron deficiency. Haemoglobin can be anticipated to begin to increase within 1-2 weeks of IV iron treatment.
Two preparations of intravenous iron (IV) are approved for IV use at Brockville Hospital ambulatory Care Program: 1- Iron sucrose (Venofer®) 2- Iron isomaltoside (Monoferric®) Refer to Table 1 for comparison information
The normal recommended dosage schedule is 100-200mg iron two or three times a week depending on the haemoglobin level. Iron Sucrose (Ferinject ® ) is a ferric carboxymaltose.
IV Iron Dosing. Total replacement dose based on calculated iron deficit: Dose in mg = actual body weight (kg) x (target Hgb – actual Hgb in g/L) x 0.24 + depot iron (mg) ₶.
4 Δεκ 2010 · This article will review the administration, indications, and safety profiles of the available IV iron preparations in the developed world. However, it is prudent to review the history of injectable iron to better understand the current reluctance to adopt routine use of IV iron therapy.
