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  1. 15 Φεβ 2021 · Immature cell markers, such as CD34 and TdT, can help to differentiate lymphoblasts from Burkitt lymphoma which, is considered a mature high grade B cell lymphoma that mimics lymphoblastic lymphoma / leukemia. Terminology. Lymphoblastic leukemia / lymphoma. Acute lymphoblastic leukemia (ALL)

    • Hematogones

      Hematogones are lymphoid appearing cells whose...

  2. 19 Ιαν 2022 · Immunogenic cell death (ICD) has emerged as a key component of therapy-induced anti-tumor immunity. Over the past few years, ICD was found to play a pivotal role in a wide variety of novel and...

  3. 8 Δεκ 2021 · Chronic lymphoproliferative disorder of NK cells (CLPD-NK) is a provisional entity listed in the 2017 WHO classification. It is a rare, heterogeneous, indolent disorder in which the number of natural killer cells in peripheral blood is constant at ≥2 × 10/L over a period of more than 6 months (Semenzato G et al. 2012; Lamy T et al. 2017).

  4. 29 Απρ 2022 · OVs in combination with CAR T-cells are promising candidates for overcoming the current drawbacks of CAR T-cell application in tumors through triggering immunogenic cell death (ICD) in cancer cells. ICD is a type of cellular death in which danger-associated molecular patterns (DAMPs) and tumor-specific antigens are released, leading to the ...

  5. 26 Νοε 2020 · ICD-associated DAMPs include surface-exposed calreticulin (CALR) as well as secreted ATP, annexin A1 (ANXA1), type I interferon, and high-mobility group box 1 (HMGB1).

  6. ICD comprises the release of damage-associated molecular patterns (DAMPs) from dying tumor cells that result in the activation of tumor-specific immune responses, thus eliciting long-term efficacy of anticancer drugs by combining direct cancer cell killing and antitumor immunity.

  7. 10 Νοε 2020 · Classifying the hematological malignancies by assigning cells to their normal counterpart and describing the nature of disease progression are entirely reliant on an accurate picture for the development of the multifarious types of blood and immune cells.

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