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The dorsal column nuclei are a pair of nuclei in the dorsal columns of the dorsal column–medial lemniscus pathway (DCML) in the brainstem. [1] The name refers collectively to the cuneate nucleus and gracile nucleus, which are situated at the lower end of the medulla oblongata.
24 Ιουλ 2023 · The gracile nucleus gives rise to second-order neurons, which contain six different types of neurons. It is situated medially to the cuneate nucleus. Together they form the medial lemniscus.
26 Ιουλ 2023 · The fibers of fasciculus gracilis reach the ipsilateral cuneatus nucleus in the caudal medulla, where they synapse with second-order neurons. These second-order neurons then cross over as internal arcuate fibers and form the medial lemniscus on the contralateral side.
Each nucleus represents the rostral termination of the fasciculus gracilis, the dorsal column spinal pathways that carry information regarding proprioception, fine tactual discrimination (stereognosis) and vibratory sensations from the lower extremities and lower trunk.
The gracile and cuneate nuclei are anterior-posterior extending columns of neurons that are present from the upper cervical spinal cord to the lower medulla (Fig. 3B).
24 Ιουλ 2023 · The gracile nucleus situates in the midline dorsal medulla at the junction of the brainstem and the spinal cord. The gracile fasciculus carries sensory input from vertebral level T6 and below and ascends into the gracile nucleus to form the gracile tubercle.
30 Σεπ 2023 · The axons of the second-order neurons, following the nucleus gracilis and cuneatus cross the midline as internal arcuate fibers, forming the medial lemniscus. This structure ascends through the brainstem to the ventral posterolateral nucleus in the thalamus and the postcentral gyrus of the parietal lobe (Schuenke et al. 2016 ; Standring 2016 ).
