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26 Δεκ 2019 · These arteries progressively lose their low-stretch bearing component, shifting load to stiffer matrix components (collagen). At the same time, arteries also lose some of their longitudinal elasticity and geometry, leading to elongation and increased tortuosity.
2 Μαΐ 2005 · The goal of this preventive strategy is to improve the precision for early detection and treatment by identifying a marker or markers for early cardiovascular disease that could serve as a surrogate for disease progression, morbid events, and the response to therapy.
Elastin is an extracellular matrix (ECM) protein with a unique biochemical structure that provides entropic elasticity, allowing the large arteries to reversibly expand and relax with every cardiac cycle.
4 Μαΐ 2021 · An arterial wall has both elastic and viscous characteristics, and pathological and degenerative changes in the wall tissue affect the viscoelastic behavior of the artery wall. The arterial viscoelasticity may provide useful information regarding the development and progression of arterial diseases.
the elastic properties, particularly of large arteries, are impaired in the presence of cardiovascular disease and risk factors such as cigarette smoking, hypertension, diabetes and ageing. Evidence is also emerging that treatment of these risk factors
1 Δεκ 2023 · Arterial stiffness data can predict target organ damage and future cardiovascular events in hypertensive patients. Thus, early detection of arterial stiffness aids in initiating preventive measures and treatment plans to protect against progression of vascular damage.
1 Μαΐ 2013 · The first techniques, developed to evaluate arterial stiffness, use indirect measurements such as pulse wave velocity or the analysis of variations in intra-arterial pressure and volume to estimate arterial stiffness.