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Arterial Elasticity as Part of a Comprehensive Assessment of Cardiovascular Risk and Drug Treatment. Jay N. Cohn, Daniel A. Duprez, Gregory A. Grandits. Abstract—Early cardiovascular disease can be identified in asymptomatic individuals by noninvasive evaluation of functional and structural abnormalities of the vasculature and heart.
26 Δεκ 2019 · Top, the typical nonlinear relation between luminal pressure and area in large elastic arteries, explained by the progressive shift in load bearing from elastin to collagen fibers. Data translate into distensibility and pulse wave velocity (PWV) with the use of the Bramwell-Hill relation.
Some materials have linear elasticity. That is, when you plot stress versus strain, you get a straight line whose slope conveys the elastic stiffness, or modulus, of the material. Like most bio logical materials, however, blood vessels exhibit nonlinear elasticity. Their elastic stiffness is not constant but increases with the magnitude of ...
Large, elastic arteries are composed of cells and a specialized extracellular matrix that provides reversible elasticity and strength. Elastin is the matrix protein responsible for this reversible elasticity that reduces the workload on the heart and dampens pulsatile flow in distal arteries.
21 Σεπ 2016 · We begin with a brief, general discussion of measurement and modeling of cardiovascular tissue viscoelasticity. We then review known viscoelastic behavior of arteries, veins, capillaries, blood...
1 Φεβ 2002 · A simplified model of arterial elasticity has been used in many studies in which measurements are confined to the circumferential direction, and elastic non‐linearity is treated by defining incremental elastic properties over a limited region of the stress strain curve that is taken to be linear (for instance, that corresponding to the part ...
2 Φεβ 2018 · We present mouse models of supravalvular aortic stenosis, autosomal dominant cutis laxa-1, and graded elastin amounts that have been invaluable for understanding the role of elastin in arterial mechanics and cardiovascular disease.