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  1. Prescribers and pharmacists check that blood tests are monitored regularly and that it is safe to issue a repeat prescription and/or dispense the prescribed lithium. Systems are in place to identify and deal with medicines that might adversely interact with lithium therapy.

  2. Lithium monitoring: Prior to starting lithium: Obtain the following to assess for pre-existing conditions: • Urinalysis • BUN/creatinine • TSH with reflexive free T4. Some suggest obtaining antithyroid peroxidase antibody titers as well. • Calcium • Pregnancy test for those with childbearing potential

  3. 31 Μαΐ 2018 · Lithium monotherapy is effective against manic, depressive, mixed relapse and suicidal behaviours. It also has better evidence for the prevention of new episodes than other agents and has more substantial evidence base documenting the risks of prolonged exposure. [Goodwin et al., 2016]

  4. The Lothian lithium guidelines include a lithium treatment plan (see Fig. 1); advice for clinicians on managing patients' lithium levels; and pointers for counselling patients on lithium (to be used in conjunction with a patient information leaflet).

  5. Guideline 03, version 1.2 Safe Use of Lithium in Adults Shared Care Protocol This protocol provides prescribing and monitoring guidance for lithium therapy. It should be read in conjunction with the HMMC shared care principles document, Summary of Product Characteristics (SPC) available on www.medicines.org.uk/emc and the BNF.

  6. Patients prescribed lithium are monitored in accordance with best practice guidance. Prescribers check that blood tests are carried out and monitored regularly and that it is safe to issue a repeat prescription.

  7. clear standards for lithium monitoring, including measure-ment of serum lithium concentrations every three months and assessment of thyroid and renal function every six months.3 These guidelines are more stringent than the cur-rent quality outcome framework targets for England. A quality improvement programme showed that mental