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In this paper, we will provide a review of the prognostic factors of malignant ascites, the pathophysiology of ascites formation, current diagnostic modalities, traditional therapeutic measures and newer therapies, including current medical and surgical treatment options.
The median survival following diagnosis of ascites was 5.7 months. Ovarian cancer favoured longer survival while low serum albumin, low serum protein and liver metastases adversely affected survival. The independent prognostic factors for survival were cancer type, liver metastases and serum albumin.
Two main reasons cause ascites in patients with cancer. First, cancer can spread to the lining of the organs—the peritoneum—and make it leaky, causing malignant ascites. Second, cancer can spread to the liver and cause increased pressure in the liver.
27 Φεβ 2024 · Malignancy-related ascites is much less common, accounting for or contributing to ascites formation in approximately 7 percent of patients [1]. Some patients have two causes for ascites formation (eg, cirrhosis plus peritoneal carcinomatosis). This topic will review malignancy-related ascites.
12 Σεπ 2023 · Ascites formation is a common complication of cancer with a significant symptomatic burden for patients. Malignant ascites (MA) is defined by the presence of tumor cells within the ascitic fluid. It does not only cause substantial morbidity, but is also associated with impaired survival.
There is limited national guidance on management of malignant ascites .This guideline has been produced to enable healthcare professionals to make evidence-based, patient-centred decisions about the management of ascites in patients with life-limiting cancer.
27 Απρ 2015 · Malignant ascites can develop through several mechanisms: blocked lymphatic channels as a result of malignancy, direct production of fluid into the peritoneal cavity by highly active cancers, and...
