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The most powerful and quickest way to restore a normal Hcy score, below 7 mcmol/l, if you’ve tested and found your level is above 10, is to supplement specific homocysteine-lowering nutrients. These include vitamins B6, B12, folic acid, trimethylglycine (TMG) and zinc, as well as glutathione or n-acetyl cysteine (NAC).
Conclusion: Further research is needed to correlate the increase in Hcy with specific symptoms/ deficits in ASD and to evaluate the clinical impact of strategies that can reduce Hcy concentration in ASD. Keywords: Autism spectrum disorder; biomarker; core symptoms; homocysteine; language development; metabolism..
CONTEXT: Children with autism spectrum disorder (ASD) frequently use special diets or abstract receive nutritional supplements to treat ASD symptoms. OBJECTIVES: Our objective was to evaluate the effectiveness and safety of dietary interventions or nutritional supplements in ASD. DATA SOURCES: Databases, including Medline and PsycINFO.
26 Δεκ 2019 · Moreover, lower GSH levels in the GI tract can promote inflammation and contribute to symptoms of GI discomfort and dysfunction. Thus, a GFCF diet may provide clinical benefit by improving CYS absorption and GSH levels, particularly in individuals with low GSH levels, as is the case in ASD.
Probiotics replenish beneficial gut bacteria, Lactobacillus Acidophillus and Bifidobacter—help break down food, make nutrients more available for absorption, relieve strain on digestive system. Amino acid glutamine aids in gut healing, but may be contraindicated in autism due to protein deanimation problems ammonia. Casein free probiotics?
Overall, an increased homocysteine level was associated with ASD in a linear manner and is thus a novel diagnostic biomarker for ASD, suggesting that homocy steine-lowering interventions or folate and vitamin B12 supplementation might be a viable treatment strategy for ASD.
The urinary levels of homocysteine and essential amino acids in both the untreated and treated autistic children are significantly less than those in the controls. The current literature suffers from many methodological shortcomings which needed to be considered in future studies.
