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5 Μαρ 2024 · Sildenafil is the main component of drugs used to treat erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio). "Our findings provide further weight to re-purposing this...
5 Μαρ 2024 · New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer’s patients.
6 Δεκ 2021 · A new Cleveland Clinic-led study has identified sildenafil – an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Revatio) – as a promising drug candidate to help prevent and treat Alzheimer’s disease.
6 Δεκ 2021 · A new Cleveland Clinic-led study has identified sildenafil -- an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Ravatio) -- as a promising drug candidate to...
6 Δεκ 2021 · A new Cleveland Clinic-led study has identified sildenafil—an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Ravatio)—as a promising drug candidate to help...
These real-world patient data validation and mechanistic observations from patient iPSC-derived neurons further suggested that sildenafil is a potential repurposable drug for AD. Yet, randomized clinical trials are warranted to validate the causal treatment effects of sildenafil in AD.
14 Δεκ 2021 · A team of researchers led by Dr. Feixiong Cheng at the Cleveland Clinic developed a computational method for identifying FDA-approved drugs that might be effective against AD. NIH’s National Institute of Aging (NIA) supported the study. Results appeared in Nature Aging on December 6, 2021.
