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  1. Primary mediastinal sarcomas are rare and deadly. Our objective was to describe the clinicopathological features, treatment strategies, and overall survival outcomes for a contemporary cohort of patients diagnosed with primary mediastinal sarcoma in the United States.

  2. 17 Ιουλ 2024 · The approach to a patient with a mediastinal mass will be reviewed here, including planning the diagnostic workup as well as initial therapy. In addition, a brief overview of the most common causes of mediastinal masses is presented.

  3. 13 Δεκ 2022 · What is the treatment for a mediastinal mass? Treatment for mediastinal tumors depends on the type of tumor, its location, its stage (if it’s cancerous) and your symptoms. Surgery is the most common treatment.

  4. A mediastinal tumor can be simulated by a mass located in the medial portion of the lung or in the pleural leaflet, adjacent to the mediastinum or diaphragm. Their distinctive radiologic densities also differentiate the mediastinal structures that are in contact with the lung.

  5. Patients with a histologic diagnosis of sarcoma (OR, 7.84; P = .044) and those with locally advanced tumors invading other structures or organs in the mediastinum (OR, 6.79; P < .001) were associated with an increased likelihood of having a composite adverse outcome.

  6. 30 Ιουν 2020 · Despite these multimodal treatment options, the prognosis for patients with mediastinal synovial sarcomas remains poor, with a median overall survival of 36 months and a 5-year overall survival rate of 35.7%, compared to a 5-year overall survival rate of 50–80% for extremity primaries (10-12,33-35). This is likely due to presentation at ...

  7. 30 Δεκ 2020 · Introduction. Primary mediastinal sarcomas represent an extremely rare and heterogenous group of mesenchymal neoplasms comprising <10% of primary mediastinal tumors and 1–2% of all soft tissue sarcomas ( 1 - 4 ).

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