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13 Ιουν 2005 · Mechanism of action. Methylergometrine acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions through binding and the resultant antagonism of the dopamine D1 receptor.
10 Φεβ 2020 · Mechanism of Action. Increases the tone, rate and amplitude of contractions on the smooth muscles of the uterus, producing sustained contractions which shortens the third stage of labor and reduces blood loss.
Methergine (methylergonovine) dosing, indications, interactions, adverse effects, and more. 0.2 mg PO q6-8hr, not to exceed 6 months. Interactions. Interaction Checker. Enter a drug name to check...
4 Απρ 2024 · Advice and warnings for the use of Methylergonovine (Methergine) during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out.
Methergine (methylergonovine maleate) acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions. Thus, it induces a rapid and...
Pregnancy . Category C. Animal reproductive studies have not been conducted with Methergine. It is also not known whether methylergonovine maleate can cause fetal harm or can affect reproductive...
Pregnancy Rating. Contraindicated during pregnancy; No known risk of teratogenicity; Risk of fetal hypoxia based on mechanism of action; Lactation risk. Avoid breastfeeding during treatment and 12 hours after discontinuing; Risk for infant vomiting, diarrhea, bradycardia, tachycardia, and seizures; Renal Dosing. Adult: Caution advised in ...
