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4 Απρ 2024 · During labor and delivery, this drug is utilized after delivery to assist involution and decrease hemorrhage. Under full obstetric supervision, this drug may be given in the second stage of labor following delivery of the anterior shoulder. There are no controlled data in human pregnancy.
This medication must not be used during pregnancy. It may harm an unborn baby. Consult your doctor for more details. This medication may decrease the amount of breast milk.
Medscape - Postpartum hemorrhage dosing for Methergine (methylergonovine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
10 Φεβ 2020 · Methylergonovine is intended for use after delivery of the anterior shoulder, after delivery of the placenta, or during the puerperium; use is contraindicated during pregnancy. Methylergonovine is recommended when a supplemental uterotonic agent is needed; due to maternal side effects it is not preferred for initial use (ACOG 183 2017).
13 Ιουν 2005 · Mechanism of action. Methylergometrine acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions through binding and the resultant antagonism of the dopamine D1 receptor.
27 Οκτ 2024 · Geriatric. Although appropriate studies on the relationship of age to the effects of methylergonovine have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.
28 Απρ 2018 · Methergine is commonly used more broadly for bleeding not only associated with pregnancy, delivery, or pregnancy loss or fetal demise, but in a variety of other medical situations most likely to prevent excessive bleeding and the associated symptomatology associated with anemia. METHODS: