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Inadvertent administration during pregnancy is followed by tetanic contractions and fetal bradycardia. Breastfeeding Safety. There are no adequate reports or well-controlled studies in nursing women. The concentrations of methylergonovine in human breast milk are clinically insignificant.
18 Δεκ 2020 · Examples of drugs used on-label during pregnancy include beta-adrenergic inhalers for relief of asthmatic bronchospasms, antiseizure medications for epilepsy, antibiotics for bacterial infections, and glucocorticoids for systemic lupus erythematosus and other autoimmune diseases.
30 Απρ 2022 · According to current evidence, oxytocin therapy combined with other uterotonics (carbetocin, methylergonovine, ergometrine, misoprostol, prostaglandin analogs, and TXA) is more beneficial than oxytocin therapy alone for the prevention of PPH, but this merits additional research.
Methergine (methylergonovine maleate) acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions. Thus, it induces a rapid and...
Pregnancy Categories. A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk. B: May be acceptable. Either animal studies show no risk but...
The objectives of this study were to quantify the prescription of oral methergin tablets in a busy Women’s Hospital, assess the stated indications for such prescription and highlight the issues and safety profile of Methergin use especially in the postpartum patient.
21 Ιουν 2023 · Discussion. The living meta-analysis approach proposed by the metaPreg project will enable direct access to synthesized results regarding the risk of drugs during pregnancy for which relevant epidemiological studies are available. The proposed project has a number of strengths.
