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How does methotrexate work? • One way methotrexate works is by decreasing the production of immune cells. What are the benefits of taking methotrexate for a person with lupus? • Methotrexate treats joint pain and swelling in lupus patients. It can also treat the butterfly rash on the face (called malar rash). It is sometimes used to treat ...
Do remember, though, that sometimes methotrexate may be used in combination with certain NSAIDs to treat lupus. Your doctor will work with you to determine which treatments will work best to treat your lupus symptoms with the fewest side effects.
8 Μαΐ 2023 · Detailed Methotrexate dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Psoriasis, Breast Cancer and more; plus renal, liver and dialysis adjustments.
30 Σεπ 2016 · Glucocorticoids are given mainly as oral prednisone, prednisolone, or intravenous high-dose methylprednisolone. Daily doses of glucocorticoids can vary among providers, and can range from 0.5 to 2 mg/kg/day. The initial dose is decided by the extent of disease severity and organ involvement.
Efficacy and safety of methotrexate in articular and cutaneous manifestations of systemic lupus erythematosus.
7 Ιαν 2014 · All of the included studies predominantly involved patients with arthritis or mucocutaneous features. There was significant reduction of the SLE Disease Activity Index (SLEDAI) among MTX-treated patients when compared with controls ( p = 0.001, odds ratio (OR) 0.444, 95% confidence interval (CI) 0.279 to 0.707).
Children—Dose is based on body size and must be determined by your doctor. At first, 10 milligrams (mg) per meter squared (m2) once a week. Your doctor may adjust your dose as needed and tolerated.
