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What are the benefits of taking methotrexate for a person with lupus? • Methotrexate treats joint pain and swelling in lupus patients. It can also treat the butterfly rash on the face (called malar rash). It is sometimes used to treat inflammation around the heart (called pericarditis) or around the lungs. How long does methotrexate take to work?
8 Μαΐ 2023 · Detailed Methotrexate dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Psoriasis, Breast Cancer and more; plus renal, liver and dialysis adjustments.
Efficacy and safety of methotrexate in articular and cutaneous manifestations of systemic lupus erythematosus.
Do remember, though, that sometimes methotrexate may be used in combination with certain NSAIDs to treat lupus. Your doctor will work with you to determine which treatments will work best to treat your lupus symptoms with the fewest side effects.
6 Οκτ 2017 · Death from active lupus is rare in the UK [15, 16]; however, a 10% mortality over 20 years and a mean age of death of 53.7 years was recently reported . About one-third of SLE patients in the UK develop LN [ 16–18 ].
7 Ιαν 2014 · All of the included studies predominantly involved patients with arthritis or mucocutaneous features. There was significant reduction of the SLE Disease Activity Index (SLEDAI) among MTX-treated patients when compared with controls ( p = 0.001, odds ratio (OR) 0.444, 95% confidence interval (CI) 0.279 to 0.707).
Conclusion: The use of MTX is associated with significant reductions in SLEDAI and the average dose of corticosteroids in adult patients with SLE. Keywords: SLE; Systemic lupus erythematosus; efficacy; lupus; methotrexate.
