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1 Οκτ 2021 · The authors discuss the use of MTX in the treatment of disorders arising from trophoblastic tissue (namely EP and GTD), its mechanism of action, its route of administration, and various treatment regimens.
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Methotrexate (MTX) is the primary pharmaceutical agent that...
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We want to discuss on which find-ings teratogenicity is based and which open questions still exist. In this context, we intro-duce a recent Italian study by Zanetti et al1 on pregnancy outcomes after therapeutic use of MTX in women with rheumatoid arthritis (RA). MTX is on the WHO list of essential medi-cines.
In this context, we introduce a recent Italian study by Zanetti et al1 on pregnancy outcomes after therapeutic use of MTX in women with rheumatoid arthritis (RA). MTX is on the WHO list of essential medicines.
1 Οκτ 1999 · Table 5 summarizes the largest prospective study of pregnancy outcome in women on MTX prior to conception. 40 It is also the only study where low-dose MTX was used within 1 year of pregnancy. A high rate of spontaneous abortion is seen (as mentioned above), but there were no abnormalities of surviving fetuses.
2 Νοε 2022 · SSZ is compatible throughout pregnancy, with folic acid 5 mg/day recommended in the periconception period and during the first trimester (GRADE 1B, SOA 100%). SSZ is compatible with breastmilk exposure in healthy, full-term infants (GRADE 1C, SOA 99.5%).
Methotrexate was used to induce abortions and is currently used to treat ectopic pregnancies (pregnancies that grow outside the uterus). Some brand names for methotrexate are: Otrexup®, Trexall®, Rheumatrex®, and Rasuvo®.
15 Μαρ 2023 · RA women treated with MTX at any time before conception showed significantly higher risks of pregnancy losses than non-RA women (OR (95% CI) 2.22 (1.40 to 3.45)).
