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11 Αυγ 2024 · Most of the toxic effects of methylprednisolone and other glucocorticoids are predictable from their impact on the body's physiology. Some are life-threatening and include metabolic effects (eg, growth inhibition, diabetes, muscle wasting, osteoporosis), salt retention (although less common with methylprednisolone), and psychosis.
3 Ιουλ 2023 · While short-term use of corticosteroids is associated with mild side effects, long-term use can result in several severe adverse effects, some of which are irreversible. This is why an interprofessional team approach to corticosteroid therapy and subsequent monitoring is necessary.
1 Μαΐ 2023 · Corticosteroid adverse effects appear to be related to both their average dose and cumulative duration. Adverse effects are more common at higher dosages and with chronic use though they are not limited to these cases. Adverse effects are seen in up to 90% of patients who take them for more than sixty days.
11 Αυγ 2024 · Methylprednisolone is an FDA-approved medication used for managing and treating various conditions, including allergic reactions, arthritis, asthma exacerbations, long-term asthma maintenance, and acute exacerbations of multiple sclerosis.
Osteoporosis, adrenal suppression, hyperglycemia, dyslipidemia, cardiovascular disease, Cushing’s syndrome, psychiatric disturbances and immunosuppression are among the more serious side effects noted with systemic corticosteroid therapy, particularly when used at high doses for prolonged periods.
17 Μαΐ 2022 · Importance: The effect of glucocorticoids on major kidney outcomes and adverse events in IgA nephropathy has been uncertain. Objective: To evaluate the efficacy and adverse effects of methylprednisolone in patients with IgA nephropathy at high risk of kidney function decline.
9 Απρ 2021 · Methylprednisolone is an option for treating ARDS. However, the benefits and adverse effects of methylprednisolone have not been well assessed in patients with ARDS. This study aimed to evaluate the efficacy and safety of methylprednisolone against ARDS.
